Selective androgen receptor modulators (SARMs) are a group of anabolic compounds that bind to androgen receptors. These compounds have been studied as potential treatments for osteoporosis, breast cancer, muscle wasting, and other diseases that cause skeletal muscle loss. SARMs are also available in dietary supplements that are marketed to bodybuilders and other athletes as a way to improve performance and build lean muscle mass. However, research on SARMs is limited as to how they affect the body long-term. In addition, dietary supplements that contain SARMs are not FDA-approved and are not regulated. This makes it very likely that what is listed on the label may not be present in the supplement, and the amount of SARM present could be inaccurate.
For example, a SARM known as RAD-140 is sold in liquid form at 10 mg/mL on many websites that claim to sell it. However, the molecule has never been clinically tested in humans for use as a treatment. The fact that it is not regulated means the liquid version of this SARM may not be safe and could contain other ingredients that could be dangerous.
Another common SARM in dietary supplements is Cardarine GW501516. This SARM is often sold in supplements that claim to boost testosterone levels, which is why it’s popular among bodybuilders. However, it’s illegal to sell or purchase a product containing Cardarine without an FDA-approved prescription in the United States. The supplements that contain this compound may not be produced in a cGMP-compliant facility, which could lead to serious side effects including liver toxicity and cardiovascular disease. sarms supplement